Pancreatic Cancer

Atypical meningioma is a tumour that arises from the lining of the brain. It mostly affects adults, with most patients in the 40-60 year age group. The primary treatment for...

SOCRATES HCC will investigate whether a radiotherapy technique (called SABR) can treat early stage liver cancer more effectively than current treatments which use heating probes directly inserted into the tumour...

Australian Particle Therapy Clinical Quality Registry (ASPIRE) is a prospective, observational, longitudinal study of paediatric, adolescent, young adult and rare adult tumour patients from a select group of tumour streams...

The ADELE clinical trial seeks to improve outcomes for people with high-risk endometrial cancer, who have a significant risk of relapse after standard post-operative treatment with chemotherapy & radiotherapy. It...

This study aims to assess the clinical benefit of local ablative therapy (LAT) following initial standard first-line systemic treatment, compared to continued standard first-line systemic treatment in patients with unresectable...

This clinical research study looked at a new combination of chemotherapy drugs (Idarubicin and Methotrexate) followed by a lower dose of radiotherapy in participants with Primary Central Nervous System Lymphoma...

Six months of hormone treatment improves the results of radiotherapy for men with early prostate cancer. This trial will determine if adding another 12 months of hormone treatment after radiotherapy...

The SEAFARER project enables clinical radiation therapy departments to assess the performance of their Patient Specific Quality Assurance (PSQA) process. PSQA, alongside other quality assurance measures, plays an important role...

People with cancer of the oesophagus (gullet) often have trouble swallowing. Radiotherapy can help improve this problem. Using chemotherapy together with radiotherapy may work better but has more side effects....

Treatment options for patients with relapsed lymphoma include standard-dose chemotherapy, radiotherapy or high-dose chemotherapy and peripheral blood stem cell transplantation. It has been found that if lymphoma recurs after transplantation...

Radiotherapy to the breast reduces the risk of cancer coming back for women with early breast cancer. This international study will determine if treating a larger area with radiotherapy can...

For patients who have undergone surgery for high-risk skin cancer of the head and neck, this study aims to determine whether there is a difference in time to loco-regional relapse...

The main aim of this study is to test the effectiveness of radiotherapy for marginal zone lymphoma that has developed outside the stomach. The treatment that is given in the...

Breast cancer is a disease that can be treated with surgery to remove the part of the breast that has the cancer followed by radiation treatment to the whole breast....

Radiotherapy for head and neck cancer may cause the lining of the mouth and throat to become inflamed and sore during treatment. This lining is called the oral mucosa and...

The purpose of this study is to assess the safety and feasibility of combining radiotherapy and carboplatin (a chemotherapy drug) with a new drug called cetuximab in patients with locally...

Locally advanced rectal cancer is a cancer of the rectum that has a high risk of recurrence. In general, patients with this condition would benefit from further treatment in addition...

The purpose of this study is to investigate whether radiotherapy given as three large doses over a period of two weeks (hypofractionated radiotherapy) is more effective than standard radiotherapy for...

Radiation therapy uses high-energy x-rays to kill tumor cells. It is not yet known which radiation therapy regimen is more effective in treating metastatic spinal cord compression. This randomised clinical...

The purpose of this study is to investigate whether adding chemotherapy to a short (less than six weeks) course of radiotherapy results in a greater improvement in symptoms and overall...

TROG 14.04 tested the feasibility of Deep Inhalation Breath Hold (DIBH) to reduce heart radiation dose in left sided breast cancer patients in a multicentre setting. Patient reported outcomes such...

Most linear accelerators used to treat cancer patients today are equipped with fixed X-ray imagers which are typically used to take images of a tumour before a patient receives radiotherapy....

For patients with stage I and II low grade follicular lymphoma radiotherapy will cure 40-50% of cases. This study is comparing standard therapy (radiotherapy) and investigational therapy (radiotherapy plus chemotherapy)...

This study is evaluating the effectiveness of a dietitian delivered health behaviour intervention to reduce malnutrition in head and neck cancer patients undergoing radiotherapy. You may be eligible to join...

Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing...

DCIS is the name for a condition in which abnormal cells are contained within the milk ducts of the breast. DCIS is not an invasive breast cancer however, if left...

There are currently two ways of managing the treatment of men who have had a radical prostatectomy. The first option is to give radiotherapy immediately after surgery to everyone. Researchers...

This study compares radiation plus chemotherapy with radiation alone in treating women with endometrial cancer that is classified as high risk or advanced stage. Participants will be divided into two...

The purpose of this study is to investigate the effect of adding whole brain radiotherapy after surgery and/or stereotactic irradiation (SI) on the development of further brain metastases (cancer spread...

This study compares the effectiveness of treatment with the drug anastrozole before and during adjuvant radiotherapy compared with anastrozole therapy delayed until after radiotherapy. This study is for woman who...

This trial is suitable for people that have been diagnosed with an unusual form of melanoma known as neurotropic melanoma. Neurotropic melanoma is characterised by the presence of melanoma cells...

This study aims to develop a well-tolerated chemo-radiotherapy treatment for patients with Merkel Cell Carcinoma (MCC) of the skin, which achieves high rates of cancer control. The researchers will be...

This trial included patients that were diagnosed with breast cancer and had the cancer completely removed by surgery (mastectomy). Patients on the trial were given anti-cancer drugs in the form...

Fit women with locally advanced breast cancer (LABC) are treated with a combination of chemotherapy, radiation treatment and surgery. There is no set order for the radiation treatment or surgery,...

Radiation treatment alone or in combination with chemotherapy can cure bladder cancer. The higher the radiation dose to the tumour the higher the chances of curing the cancer, however, higher...

The drug nimorazole belongs to a class of chemicals known as 5-nitroimidazoles. Drugs from this class are used against infection. In addition, nimorazole makes tumour cells more sensitive to radiotherapy....

Surgery is the standard treatment for primary kidney cancer, however, in some cases surgery is either not possible or other health problems make surgery high risk. This study involves a...

The aim of this study is to determine the activity and safety of treating an asymptomatic, extrapulmonary metastasis with a single fraction of SABR, during immunotherapy with nivolumab in advanced...

CORE is a phase II/III, multicentre, non-blinded, randomised controlled trial in patients with breast, prostate or non-small cell lung cancer (NSCLC) primary cancer to evaluate if the addition of stereotactic...

The FIG trial is investigating how the addition of FET-PET imaging to standard MRI imaging affects radiation target volume delineation and treatment planning for Glioblastoma, as well as determining the...

The 90 patients in this trial were randomised into two groups – half received a single high-dose of stereotactic ablative radiotherapy or SABR, and the other had an equivalent dose...

Stereotactic Ablative Body Radiotherapy (SABR) is an established treatment for both primary and secondary liver malignancies and is a highly effective treatment, but precise dose delivery is challenging due to...

For patients who have HER2 positive breast cancer which has spread to the brain (metastasised) the main treatment options for these brain metastases are as follows: Whole Brain Radiotherapy (WBRT),...

The current standard of care for patients with early breast cancer is radiation therapy (RT) after breast conserving surgery to improve cancer control. However, breast cancer is a complex disease,...

CHEST RT is investigating the safety and effectiveness of combining chemotherapy and immunotherapy with chest radiation therapy for the treatment of extensive stage small cell lung cancer (ES-SCLC). For over...

In the era of PET imaging, many sites of disease that are not visible on conventional imaging will be found on PSMA (prostate specific membrane antigen) PET. For men with...

The aim of the trial is to assess the benefit of adding high precision radiation therapy to chemotherapy and surgery for the treatment of pancreatic cancer.

20-40% of patients with NSCLC will develop brain metastases at some point during their course of the disease. Osimertinib has demonstrated intracranial activity in EFGR mutated NSCLC with leptomeningeal disease...

The aim of this trial is to investigate whether pre-operative treatment with chemotherapy plus radiation therapy has a better outcome than chemotherapy alone in patients undergoing surgery for resectable gastric...

Triple-negative breast cancer (TNBC) is a subtype of breast cancer that lacks the expression of oestrogen (ER) and progesterone (PR) receptors and lacks overexpression or amplification of the HER2/NEU gene....

In men with intermediate and high-risk prostate cancer, the NINJA trial is looking at comparing two different radiotherapy treatment schedules called stereotactic body radiotherapy (SBRT). The aim is to develop...