A phase II study of local therapy only (stereotactic radiosurgery and or surgery) for treatment of up to 5 brain metastases from HER2+ breast cancer

For patients who have HER2 positive breast cancer which has spread to the brain (metastasised) the main treatment options for these brain metastases are as follows: Whole Brain Radiotherapy (WBRT), or Stereotactic Radiosurgery (SRS), or Neurosurgery (NS) This study aims to show that brain metastases are able to be controlled by SRS and/or NS without the need for WBRT.

Primary Sponsor

Trans-Tasman Radiation Oncology Group (TROG)

Participating Centres

Accrual Target


Current Accrual

Closing Date of Accrual

22nd December 2020

Trial Chairperson

Dr Claire Phillips, Peter MacCallum Cancer Centre, VIC

Trial Contact


Clinical Trial Registration

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