For patients who have HER2 positive breast cancer which has spread to the brain (metastasised) the main treatment options are as follows: Whole Brain Radiotherapy (WBRT), or Stereotactic Radiosurgery (SRS), or Neurosurgery (NS).

The aim of this study was to show that brain metastases are able to be controlled by SRS and/or NS without the need for WBRT. Although a modest sample size, study results show that Stereotactic radiosurgery (SRS) and/ or neurosurgery, provided good control with low toxicity for patients with metastatic HER2+ breast cancer brain metastases.

Link to publication: doi: 10.1016/j.breast.2024.103675