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Open Trials – In Follow Up

TROG Cancer Research radiation therapy trials in follow up, are those trials that are fully approved and have now accepted the required number of participants. These participants are receiving active treatment and/or care by their doctors, with trial data still being collected.

Results of these trials will be made available once all participants have completed care and trial data is finalised. 

BIG 307/TROG 07.01 – DCIS

A randomised phase III study of radiation doses and fractionation schedules in non-low risk ductal carcinoma in-situ (DCIS) of the breast

TROG 08.06 – STARS

A Randomised comparison of anastrozole commenced before and continuing during adjuvant radiotherapy for breast cancer versus anastrozole and subsequent anti-oestrogen therapy delayed until after radiotherapy.

TROG 12.02 – PET LABRADOR

PET scans for locally advanced breast cancer and diagnostic MRI to determine the extent of operation and radiotherapy

TROG 15.03/ANZUP 16001 – FASTRACK II

Focal Ablative STereotactic RAdiosurgery for Cancers of the Kidney - a Phase II Clinical Trial

TROG 20.01 – CHEST RT

Chemotherapy Immunotherapy in Extensive Stage Small Cell with Thoracic Radiation therapy

USYD/TROG 17.03 – LARK

Liver Ablative Radiotherapy utilizing Kilovoltage intrafraction monitoring (KIM)

EORTC 13.08/TROG 15.02 – ROAM

Radiation versus Observation following surgical resection of Atypical Meningioma: a randomised controlled trial

EORTC 22033-26033/TROG 06.01 (Low Grade Glioma)

Primary chemotherapy with temozolomide vs. radiotherapy in patients with low grade gliomas after stratification for genetic 1p loss: a phase III study

ICR-CTSU/2015/15552/TROG 16.03 – CORE

A randomised trial of Conventional care versus Radioablation (stereotactic body radiotherapy) for Extracranial oligometastases

TROG 14.02 – RAIDER

A randomised phase II trial of adaptive image guided standard or dose escalated radiotherapy in the treatment of transitional cell carcinoma of the bladder

AGITG AG0407GR/TROG 08.08 – TOPGEAR

A randomised phase II/III trial of preoperative chemoradiotherapy versus preoperative chemotherapy for resectable gastric cancer.

ANZUP 1801/TROG 21.02 DASL-HiCaP

Darolutamide Augments Standard Therapy for Localised Very High-Risk Cancer of the Prostate. A randomised phase 3 double-blind, placebo-controlled trial of adding darolutamide to androgen deprivation therapy and definitive or salvage radiation in very high risk, clinically localised prostate cancer.

R2810-ONC-1788/TROG 17.11 – CPOST

A randomised, placebo-controlled, double-blind study of adjuvant Cemiplimab versus placebo after surgery and radiation therapy in patients with high risk cutaneous squamous cell carcinoma

TROG 14.01 – ENZARAD

Randomised phase 3 trial of radiation plus androgen deprivation therapy with or without enzalutamide for high risk, clinically localised, prostate cancer

E33039 IAEA NPC

A Situation Analysis of National Radiotherapy Resources and Patterns of Care for Patients with Nasopharyngeal Carcinoma in Low-Middle Income Countries: Can Enhancing the Quality of Radiotherapy Planning Improve Outcomes