A randomised, placebo-controlled, Phase II trial of adjuvant Avelumab in patients with stage I-III Merkel cell carcinoma

I-MAT will determine if a six-month treatment regime of Avelumab is well-tolerated and can eliminate residual microscopic cancer cells, thus reducing the risk of the cancer reoccurring and improving the overall outcomes for patients with early-stage Merkel cell carcinoma.

Primary Sponsor

Melanoma and Skin Cancer Trials Limited (MASC Trials)

Collaborating Groups

Trans Tasman Radiation Oncology Group (TROG)

Accrual Target

132

Final Accrual

122

Expected Date of Accrual

June 2024

Trial Chairperson

Dr Wen Xu, Princess Alexandra Hospital, QLD, Australia

Trial Contact

imat@masc.org.au

Related Post

Myall Coast Veteran Golfers fundraiser for TROG
12 November, 2025

Veterans golf club swings behind TROG Cancer Research

LATEST NEWS: 12 November 2025 More than 100 golfers

SUPREMO breast cancer trial results published in NEJM
6 November, 2025

SUPREMO trial findings signal change in breast cancer treatment

LATEST NEWS: 6 November 2025 Radiotherapy can be safely