ADjuvant tislelizumab plus chemotherapy after post-operative pelvic chemoradiation in high risk EndometriaL cancer (ADELE): a randomised phase 2 trial

The ADELE clinical trial seeks to improve outcomes for people with high-risk endometrial cancer, who have a significant risk of relapse after standard post-operative treatment with chemotherapy & radiotherapy. It is hoped that this study may improve relapse rates in high-risk endometrial cancer by adding Tislelizumab immunotherapy to standard treatment.

Primary Sponsor

Australia New Zealand Gynaecological Oncology Group (ANZGOG)

Collaborating Groups

Trans Tasman Radiation Oncology Group (TROG)

Accrual Target

135

Expected Date of Accrual

March 2025

Trial Chairperson

Professor Linda Mileshkin, Peter MacCallum Cancer Centre, VIC, Australia

Dr Yeh Chen Lee, NHMRC Clinical Trials Centre & Prince of Wales Hospital

Trial Contact

qa@trog.com.au

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