Randomised Phase II Trial to Evaluate the Strategy of Integrating Local Ablative Therapy with First-Line Systemic Treatment for Unresectable Oligometastatic Colorectal Cancer

This study aims to assess the clinical benefit of local ablative therapy (LAT) following initial standard first-line systemic treatment, compared to continued standard first-line systemic treatment in patients with unresectable oligometastatic CRC.

Primary Sponsor

Australasian Gastro-Intestinal Trials Group (AGITG)

Collaborating Groups

Trans Tasman Radiation Oncology Group (TROG)

Accrual Target

50

Final Accrual

6

Expected Date of Accrual

31 December 2026

Closing Date of Accrual

31 December 2025

Trial Chairperson

Dr Julie Chu, Peter MacCallum Cancer Centre, VIC, Australia

Trial Contact

qa@trog.com.au

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