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Breast cancer trials in development

Our breast cancer trials focus on the effects and benefits of radiation therapy as a treatment.

TD 17.05 (AZTEC) - The aim of this study is to compare the different SABR (Stereotactic Ablative Body Radiotherapy) schedules (Arm 1 and Arm 2) and which schedule is more effective in treating TNBC

Primary sponsor: TROG
Collaborative Group: Centre for Biostatistics and Clinical Trials (BaCT)

TROG 16.02 (LOCAL HER-O)  - This study aims to show that brain metastasis, from HER2 positive breast cancer, are able to be controlled by Stereotactic Radiosurgery and/or Neurosurgery without the need for WBRT

Primary Sponsor: TROG

TROG 14.04 (HART) - the aim of the HART trial is to implement the Deep Inhalation Breath Hold (DIBH) technique in Australian treatment centres for patients with left-sided breast cancer, to determine whether the technique can reduce radiation to the heart.

Primary sponsor: TROG
Collaborative Group: Australia and New Zealand Breast Cancer Trials Group (ANZBCTG)

More about breast cancer and our trials

What is breast cancer?

Breast cancer is the result of abnormal cells grouping together and growing uncontrollably. There are many different types of breast cancer, and can be treated depending on the stage and type of cancer.

What is a clinical trial?

A clinical trial is a research study which explores whether certain medical treatments are effective in preventing, detecting, treating or managing a disease or medical condition. Our breast cancer research trials help us develop a better understanding of treating breast cancer and improving treatments.

How do I participate in TROG trials?

You can discuss your suitability for a trial with your doctor or oncologist, or you can see more information below on breast cancer trials and contact the nearest participating centre.

About TROG's work with breast cancer research

One of our trials (TROG 03.05 MA.20) was revolutionary in the way breast cancer has been treated. Radiotherapy for breast cancer is a common treatment method, and the results of our trial demonstrated that radiotherapy to the lymph nodes was more effective in treating cancer than radiation to the breast only. Results of this trial proved that lymph node radiation was effective in decreasing the risk of cancer returning to other organs in the body.


We are thankful to our 14,500 patients who have participated in our research. Please continue the generous support.