TROG 15.03/ANZUP 16.01 – FASTRACK II

Dataset Name:

TROG 15.03 / ANZUP 16.001 Focal Ablative STereotactic RAdiosurgery for Cancers of the Kidney – A Phase II Clinical Trial (FASTRACK II)

DOI:

TBC

Publisher:

TROG Cancer Research

Creator(s):

Shankar Siva

Contributor(s):

N/A

Date made available:

2025

Dataset:

Individual Participant Data

Subject (ANZSRC Category):

Radiation therapy

Patient sample size:

71

Dataset Description:

This dataset includes data for 71 trial participants (50 male, 21 female) with renal cell carcinoma, taking part in the single arm, phase II FASTRACK study.

Participants were recruited at sites in 7 Australian sites and 1 international site (MAASTRO), and includes data from beginning of study through to 96 month follow up. The study commenced in Aug 2016 and conducted the last patient last visit in April 2025.

Dataset includes Timepoints from baseline to 96 months follow-up, tumour imaging, disease progression and AEs. Cancer Australia demographic data
– Postcode of home of address
– Aboriginal or Torres Strait Islander status (or Ethnicity)
– Culturally and Linguistically Diverse (CALD) status: Country of Birthn Main language other than English used as the principle means of communication.

Radiotherapy quality assurance data collected includes 11 benchmarking reviews, 71 pre-RT plan review, 69 post-RT plan review, 16 MRI substudy scans (baseline, 3, 12 months), split renal function scans (baseline, 12, 24, 42, 60 months)

Funding:

Cancer Australia, VARIAN Medical Systems

Keywords (MeSH):

kidney, cancer, fastrack, trog

ANZCTR Reference:

12615001181594

Publications:

Stereotactic ablative body radiotherapy for primary kidney cancer (TROG 15.03 FASTRACK II): a non-randomised phase 2 trial
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(24)00020-2/abstract

Requests for Data:

Access can be requested via the Health Data Australia catalogue. Search for the ACTRN number in the catalogue to find datasets associated with this trial or email enquiries to trials@trog.com.au