TROG 14.04 – HART Dataset

Dataset Name:

TROG 14.04 Deep Inhalation Breath Hold for reduction of cardiac toxicity in patients with left sided breast cancer undergoing radiotherapy (Heart Avoiding Radiation Therapy, HART)

DOI:

10.58118/v7jq-h986

Publisher:

TROG Cancer Research

Creator(s):

Prof Tomas Kron

Contributor(s):

NA

Date made available:

2023

Dataset:

Individual Participant Data

Subject (ANZSRC Category):

Radiation therapy

Patient sample size:

62

Dataset Description:

– Feasibility of Deep Inhalation Breath Hold (DIBH)
– Dose-volume parameters for the ipsilateral lung, left anterior descending artery, contralateral breast and oesophagus.
– Reproducibility of the breath-hold.
– Guidelines for quality assurance for the use of DIBH.
– Resource requirements for DIBH
– Resource use: health care professional time, equipment and consumables required to plan and deliver one episode of DIBH
– Imaging Data: CT
– Anxiety Assessment Visual Analogue Scale (VAS): Pre and Post-treatment planning CT, Pre and Post each radiotherapy fraction
– Patient Reported Experience of Breath Hold Questionnaire (DIBH participants only): Pre and Post planning CT, Pre and Post the first fraction and last week of radiotherapy treatment
– Patient Reported Outcome Completion and Missing Data (CoMiDa) Checklist
– Approx Time Period of data collection: 2018-2019

Radiotherapy Quality Assurance
– 60 participants RTQA/Imaging Dataset: RT plan, RT delivery and Imaging documentation plus EPIs (DICOM format)

Funding:

Breast Cancer Trials Group, Gross Foundation

Keywords (MeSH):

Breast Neoplasms/radiotherapy; Breath holding; Feasibility Stuides; Female; Heart; Humans; Organs at Risk; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted/methods; Reproducibility of Results; Unilateral Breast Neoplasms/radiotherapy

ANZCTR Reference:

ACTRN12617000237381

Publications:

TROG 14.04: Multicentre Study of Feasibility and Impact on Anxiety of DIBH in Breast Cancer Patients
https://www.clinicaloncologyonline.net/article/S0936-6555(22)00269-2/fulltext

Requests for Data:

Access can be requested via the Health Data Australia catalogue. Search for the ACTRN number in the catalogue to find datasets associated with this trial or email enquiries to trials@trog.com.au

Please submit a New Trial Proposal Application (Category D) to the TROG Cancer Research Operations Executive Committee.