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TROG 16.02 (Local HER-0)

Primary sponsor: Trans Tasman Radiation Oncology Group (TROG)


A phase II study of local therapy only (stereotactic radiosurgery and/or neurosurgery) for treatment of up to 5 brain metastases from HER2+ breast cancer


For patients who have HER2 positive breast cancer which has spread to the brain (metastasised) the main treatment options for these brain metastases are as follows:

  • Whole Brain Radiotherapy (WBRT), or
  • Stereotactic Radiosurgery (SRS), or
  • Neurosurgery (NS)

This study aims to show that brain metastases are able to be controlled by SRS and/or NS without the need for WBRT. 

Trial chairperson

Dr Claire Phillips, Peter MacCallum Cancer Centre, VIC

Trial contact

TROG Trial Coordinating Centre
Phone: +61 2 4014 3911

Further information

TROG trial 16.02 on Australian Cancer Trials website

Trial resources for TROG members

TROG 16.02 member page

We are thankful to our 14,500 patients who have participated in our research. Please continue the generous support.