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TROG 08.06 (STARS)

Primary sponsor: Trans Tasman Radiation Oncology Group (TROG)


STudy of Anastrozole and Radiotherapy Sequencing


This study compares the effectiveness of treatment with the drug anastrozole before and during adjuvant radiotherapy compared with anastrozole therapy delayed until after radiotherapy.

This study is for woman who have had a mastectomy or lumpectomy for breast cancer, and all planned surgery is now complete and radiotherapy is recommended.

Participants will be divided into two groups. One group will receive anastrozole orally before and during radiotherapy. The other group will receive standard treatment, where anastrozole and subsequent anti-oestrogen therapy is delayed until after radiotherapy. Participants will be monitored for 10 years after radiotherapy.

The study aims to determine if commencement of anastrozole before radiotherapy results in improved local control of the disease.

Final Accrual


Trial Status

Closed to accrual, November 2016

Trial chairperson

Prof Peter Graham, St George Clinical Trials Unit, St George Hospital, NSW 

Trial contact

Ms Helen Cox
St George Clinical Trials Unit
Phone: +61 2 9113 1922

Further information

TROG 08.06 on Australian Cancer Trials website

Trial resources for TROG members

TROG 08.06 member page

We are thankful to our 14,500 patients who have participated in our research. Please continue the generous support.