TROG 14.04 (HART)

Primary sponsor: Trans Tasman Radiation Oncology Group (TROG)
Collaborating groups: Australian and New Zealand Breast Cancer Trials Group (ANZBCTG)

Title

Deep Inhalation Breath Hold for reduction of cardiac toxicity in patients with left sided breast cancer undergong radiotherapyTherapy

Summary

TROG 14.04 tested the feasibility of Deep Inhalation Breath Hold (DIBH) to reduce heart radiation dose in left sided breast cancer patients in a multicentre setting. Patient reported outcomes such as anxiety associated with holding their breath were also investigated in comparison to right-sided breast cancer patients treated in free breathing (normal breathing).

The study confirmed that DIBH has the potential to reduce the radiation dose to the heart for left sidedbreast cancer patients receiving radiotherapy in a variety of settings.

There was a slightly higher anxiety scores among DIBH patients suggest the act of breath holding, or knowledge of the purpose of DIBH, may increase patient anxiety. However, this increased anxiety reduced to levels similar to the control group of right sided breast cancer patients throughout the course of their treatment.

Final accrual

Trial status

Closed to follow up 21/12/2018

Trial chairperson

Professor Tomas Kron, Peter MacCallum Cancer Centre, VIC

Trial contact

Rebecca Montgomery
Clinical Trial Coordinator
TROG Trial Coordinating Centre
Phone: +61 2 4014 3900
Email: HART@trog.com.au

Trial resources for TROG members

TROG 14.04 HART member page

We are thankful to our 14,500 patients who have participated in our research. Please continue the generous support.

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