TROG 08.02 (GBM in elderly patients)
Primary sponsor: NCI CTG (CE.6)
Collaborating groups: TROG
A study of temozolomide and short-course radiation versus short-course radiation alone in the treatment of newly diagnosed glioblastoma multiforme in elderly patients
Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving radiation therapy together with temozolomide may kill more tumor cells. It is not yet known whether radiation therapy and temozolomide are more effective than radiation therapy alone in treating glioblastoma multiforme (GBM).
This trial is studying radiation therapy and temozolomide to see how well they work compared with radiation therapy alone in treating patients with newly diagnosed GBM.
560 (including 97 Aus/NZ TROG sites)
Closed January 2014
Dr Claire Phillips, Peter MacCallum Cancer Centre, VIC
Dr Mike Fay, Royal Brisbane Hospital, QLD
Peter MacCallum Cancer Centre
Trial resources for TROG members
TROG 08.02 member page