Primary sponsor: EORTC
Collaborating groups: TROG, NCIC, MRC-NCRI, Brain Tumour Group
Radiation Therapy or Temozolomide in Treating Patients With Gliomas
Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. At the time of writing this protocol it was not known whether radiation therapy was more effective than temozolomide in treating gliomas.
The purpose if this randomized phase III trial was to study radiation therapy to see how well it works compared to temozolomide in treating patients with gliomas.
EORTC: 707 registered / EORTC 473 randomised
TROG: 69 registered / TROG 40 randomised
Closed to accrual, March 2010
Dr Gail Ryan, Peter MacCallum Cancer Centre, VIC
TROG Trial Coordinating Centre
Phone: +61 2 401 43903
Trial resources for TROG members
TROG 06.01 member page